Chronic Erythrocytic Hypoplasia following Pernicious Anemia.

Unique sequence of pernicious anemia, polycythemia, and acute leukemia.

nicious anemia and polycythemia, or of pernicious anemia and acute myeloblastic leukemia, is extremely rare. Wintrobe’ notes only four instances imi which pernicious anemia preceded the onset of acute myeloblastic leukemia. Polycythemia following pernicious anemia is of equal rarity.’ ‘ 2 On the other hand, the emergence of acute leukemia in cases of polycythemia, while uncomiimon, is miot as r...

Slowly progressive type 1 diabetes mellitus associated with vitiligo vulgaris, chronic thyroiditis, and pernicious anemia.

A 81-year-old woman was diagnosed as having diabetes mellitus (DM) at 58 years of age. She started insulin therapy the following year, but her blood sugar levels were poorly controlled. At the age of 75, she tested positive for the anti-GAD antibody (7.8 U/ml) and was diagnosed as having slowly progressive type 1 DM (SPIDDM), as well as vitiligo vulgaris. At 78 years of age, chronic thyroiditis...

Incidental Finding of Megaloblastic-like Cells in Bone Marrow of One of Two Swine with Macrocytic Anemia and Achlorhydria *†

Ever since Ehrlich described the megaloblasts seen in pernicious anemia during relapse, there have been attempts by many investigators to produce experimentally an anemia similar in all respects to human pernicious anemia. Macrocytic anemia with the megaloblastic type of erythrocytic regeneration in the bone marrow, achlorhydria, and a specific response to a substance containing the anti-anemic...

Anemias beyond B12 and iron deficiency: the buzz about other B's, elementary, and nonelementary problems.

The term "unexplained anemia" appears frequently in a request for a hematology consultation. Although most anemia consultations are fairly routine, they occasionally represent challenging problems that require an amalgam of experience, insight, and a modicum of "out-of-the-box" thinking. Problem anemia cases and pitfalls in their recognition can arise for one of several reasons that are discuss...

The kinetics of intravenously injected radioactive vitamin B12: studies on normal subjects and patients with chronic myelocytic leukemia and pernicious anemia.